Business Introduction
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success. We’re uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D

Position Summary

Cancer is unrelenting, but so are we. At GSK, we are committed to transforming outcomes for people with cancer through innovative science, bold ambition, and strong partnerships across the healthcare ecosystem. We focus our science where it can matter most — advancing care in cancers with high unmet need, grounded in a deep understanding of disease biology and deliberate scientific choices that connect discovery to meaningful impact in the real world.

The Clinical Development Lead (CDL) – Oncology operates at the asset level as the enterprise clinical strategy leader, accountable for defining the clinical strategy, scientific narrative, and decision framework across the asset lifecycle. The CDL serves as a full strategic partner within the Medicine Development Team (MDT) core quad, positioning Clinical Development at the centre of product strategy, governance, and investment decisions.

The CDL owns the clinical roadmap and serves as the recognised clinical authority and visible leader for the asset’s strategic vision, shaping how clinical strategy, scientific insight, development innovation, and decision velocity are understood and experienced across the organisation, representing Clinical Development in both internal and external settings. The CDL is accountable for the strategic direction and clinical positioning of the asset, with operational study-level delivery led by Senior Scientists within the programme. This role is critical to enabling a more dynamic, data-driven, and technology-enabled model of clinical development, increasing speed, precision, and decision quality.

The position is open to candidates from either a medical or non-medical background. MD, PharmD, PhD, or equivalent advanced degree is required; an MD or equivalent clinical doctorate is preferred. Depth of oncology clinical development expertise and enterprise-level leadership experience are what matter most.

In This Role You Will:

• Define and own the clinical strategy, scientific narrative, integrated benefit–risk position, and decision framework across the asset, ensuring a coherent and differentiated clinical position throughout the lifecycle
• Accountable for strategic outcomes across the asset, with study-level delivery, including design, execution, and data generation, led by Senior Scientists and programme teams within the CDL’s strategic direction
• Serve as the senior clinical strategy leader on the MDT core quad, acting as a full strategic partner to the Medicine Development Leader (MDL) and representing Clinical Development in portfolio, governance, and investment decisions
• Lead or co-lead governance and investment presentations to senior management, translating clinical evidence into clear strategic recommendations for portfolio prioritisation and progression
• Serve as the recognised clinical authority and visible leader for the asset, ensuring its clinical vision, scientific identity, and development trajectory are clearly understood and advanced across the organisation
• Drive an integrated, end-in-mind approach to development, ensuring that target selection, development pathways, regulatory positioning, and commercial readiness are considered as a connected whole
• Act as the default Clinical Development representative for Health Authority interactions, advisory boards, steering committees, IDMCs, and alliance partnerships
• Leverage AI-enabled insights, advanced analytics, and emerging data platforms to inform asset-level strategic decisions and drive competitive advantage in development speed and decision quality
• Lead, develop, and mentor clinical development talent, contributing to talent calibration, succession planning, and capability building aligned to evolving development models

Responsibilities
This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

· Medical degree, PharmD, or PhD required

· Oncology clinical development experience in the pharmaceutical industry or relevant scientific, medical, or clinical experience.

· Demonstrated experience operating at the asset, portfolio, or enterprise level, including governance and investment decision-making

· In-depth knowledge of GCP, ICH, FDA, EMA, NICE, and relevant regulatory frameworks

· Proven ability to lead and influence cross-functional teams in complex matrix environments

· Strong understanding of clinical development, oncology therapeutic landscapes, and drug approval processes

· Experience leveraging data, advanced analytics, or emerging technologies to inform clinical decision-making

Preferred Qualification
If you have the following characteristics, it would be a plus:

• If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $242,250 to $403,750. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at UKRecruitment.Adjustments@gsk.com where you can also request a call.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide.

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